Postdoc

R RIVM Postdoc: Immune development in infants Bilthoven - route • Op locatie • Overheid & Non-Profit €3.496 - €5.535 / mnd 32 - 36 uur/week Tijdelijk contract Geen specifiek diploma vereist Medior (2-5 jaar) Deze vacature is overgenomen van een externe bron. De rol Functieomschrijving Een helder overzicht van de functie, werkomgeving en belangrijke details. Would you like to apply cutting-edge single-cell RNA sequencing to uncover why some infants respond better to vaccines or are more susceptible to infections? As a postdoctoral researcher at RIVM, you will research how the infant immune system develops and why responses to vaccines vary in early life. Working at the intersection of laboratory science, computational biology, and clinical research, you will build a broad repertoire across both wet lab techniques and data science. Your research will inform national public health strategies and help protect newborns during their most critical developmental window. In their first year of life, infants build the foundation for lifelong immunity, while transitioning away from the temporary protection of maternal antibodies. As this passive immunity wanes, infants encounter environmental microbes and receive their routine childhood vaccinations. You will address a key gap in this field: despite the critical importance of this early developmental window, surprisingly little is known about how immune cells evolve over time in healthy, term-born infants, or how clinical and demographic factors shape these trajectories. During this crucial phase, you will study how their immune system learns to fight off harmful pathogens while safely establishing a healthy microbiome and maintaining tolerance to beneficial microbes. As a postdoctoral researcher in this project, you will be involved in the full experimental and analytical workflow. In this position, you will work with cutting-edge single-cell RNA sequencing technologies in a highl...

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